DFG-Subject - Advanced Projects

A system for the
declarative description and
efficient search of hybrid patterns
in large genomic data sets

This project is supported by a grant from the "Deutsche Forschungsgemeinschaft". It is part of the special program on Computational Methods for the Analysis and Interpretation of large genomic data sets.

Abstract


This project is a collaboration of the Institute for Biophysics at the University of Düsseldorf and the Technical Faculty at the University of Bielefeld.

Project Team

Institut für Physikalische Biologie
Heinrich-Heine-Universität Düsseldorf
Universitätsstraße 1, Gebäude 26.12.U1
D-40225 Düsseldorf
Germany

Dr. Gerhard Steger
steger@biophys.uni-duesseldorf.de
Phone: +49-211-81-14927
Fax: +49-211-81-15167
    Development of bioinformatic tools
      Thermodynamic stability of double-stranded nucleic acids
      Thermodynamic Prediction of Conserved Secondary Structure in RNA
      Thermodynamic stability of single-stranded nucleic acids
      Kinetic/sequential folding of single-stranded nucleic acids
      Search for and description of hybrid patterns
    Biophysics/Bioinformatics
      Thermodynamics and kinetics of nucleic acids
    Methods
      Temperature-gradient gel-electrophoresis (TGGE)
      Optical denaturation curves
      Hydrodynamics
    Objects
      Viroids
      Viral RNAs
      Ribozymes

Stefan Gräf
graef@biophys.uni-duesseldorf.de
Phone: +49-211-81-14927
Fax: +49-211-81-15167
AG Praktische Informatik
Technische Fakultät
Universität Bielefeld
Postfach 10031
D-33501 Bielefeld
Germany
Dr. Stefan Kurtz
kurtz@techfak.uni-bielefeld.de
Phone: +49-521-106-2906
Fax: +49-521-106-6411
    Data Structures and Algorithms and their Efficient Implementation
    Approximate Patterns
    Index Structures for Sequences (e.g. Suffix trees)
    Structural Patterns (e.g. repeats and palindroms)
    Implementation of Programming Languages
Dirk Strothmann
dirks@techfak.uni-bielefeld.de
Phone: +49-521-106-2914
Fax: +49-521-106-6411
    Combinatorics
    Information Theory
    Hybrid Patterns

Dirk Strothmann
Last modified: Wed Apr 21 14:32:32 MET 2004