|
|
|||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||
|
|
|||||||||||||||||||||||||||||||||
|
AGenDA - Alignment-based Gene Detection Algorithm - Version 1.0AGenDA is a gene-prediction tool that is based on cross-species sequence comparison. The software tools CHAOS and DIALIGN are used to align a pair of syntenic genomic sequences, e.g. from human and mouse. AGenDA searches for conserved splice sites and start/stop codons at the boundaries of identified sequence homologies in order to identify potential exons; these potential exons are then used to assemble entire gene models.
Users of AGenDA at BiBiServ are requested to cite:
O. Rinner and B. Morgenstern (2002) AGenDA: Gene prediction by comparative sequence analysis. In Silico Biology 2, 195-205. L. Taher, O. Rinner, S. Gargh, A. Sczyrba, M. Brudno, S. Batzoglou, B. Morgenstern (2003) AGenDA: Homology-based gene prediction Bioinformatics 19(12), 1575-1577. |
|
||||||||||||||||||||||||||||||||
|
|
|
||||||||||||||||||||||||||||||||