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AGenDA - Alignment-based Gene Detection Algorithm - Version 1.0AGenDA is a gene-prediction tool that is based on cross-species sequence comparison. The software tools CHAOS and DIALIGN are used to align a pair of syntenic genomic sequences, e.g. from human and mouse. AGenDA searches for conserved splice sites and start/stop codons at the boundaries of identified sequence homologies in order to identify potential exons; these potential exons are then used to assemble entire gene models. The
BiBiServ team discontinued the online service for AGenDA. AGenDA
doesn't run on our current server environment anymore due to a
new hardware archicture / OS upgrade. Please contact the author
of AGenDA for any questions concerning AGenDA.
Users of AGenDA at BiBiServ are requested to cite:
O. Rinner and B. Morgenstern (2002) AGenDA: Gene prediction by comparative sequence analysis. In Silico Biology 2, 195-205. L. Taher, O. Rinner, S. Gargh, A. Sczyrba, M. Brudno, S. Batzoglou, B. Morgenstern (2003) AGenDA: Homology-based gene prediction Bioinformatics 19(12), 1575-1577. |
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