Welcome to KnotInFrame

KnotInFrame is a pipeline to predict ribosomal -1 frameshift sites with a simple pseudoknot as secondary structure in DNA and RNA sequences. The prediction is based on a comparison between the minimal free energy (mfe) structure calculated by RNAfold from the Vienna package and the mfe-structure computed by a modified version of pknotsRG-mfe, called pknotsRG-frameshift developed by J. Reeder/R.Giegerich.

Note: This project is still under development, so feel free to contact us with comments and suggestions