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Table for Technical Appendix
Diagnostic sites for six groups of vertebrate serpin proteins,
computed using, according to the
list of sequences,
the sequences 1-3 & 5-12 for Group 1, 17-21 & 23-47 &
56-60 for Group 2, and all the
sequences
for the remaining groups.
Column 1 lists the six groups of vertebrate serpin proteins and the
Column 2 lists, for Groups 1 to 4, all amino acid sites that
discriminate the group in question when compaired with the other 3
ones from the first four groups. For Groups 5 and 6 (encompassing too
few sequences to allow a definitive judgement) only some
discriminating sites are listed that discriminate this group from all
other groups.
The amino acid sequence numbering system for mature human
alpha1-antitrypsin is used (and the corresponding sites from our
multiple alignment are added in square brackets [...]).
| List of single groups |
Numbers of corresponding diagnostic positions |
| 1 |
271 [700], 388 [867], 390 [869] |
| 2 |
160 [558], 187 [593] |
| 3 |
65 [409], 210 [617], 232 [644], 237 [655], 258 [679], 261 [688] |
| 4 |
110 [504], 177 [583], 226 [634], 240 [658], 260 [687], 263 [690],
267 [696], 297 [740], 333 [795], 389 [868] |
| 5 |
65 [409], 110 [504], 297 [740] |
| 6 |
231 [643], 271 [700], 297 [740] |
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